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![]() ![]() Regarding other treatments, only one study for each method fitted the inclusion criteria, so the evidence was very limited.Ĭonclusion: Topical CAIs, oral CAIs and local steroids are effective in treating RP-CME. The effects of anti-VEGF reagents varied among studies. CAIs and local steroids were proved to be effective in reducing CMT. Treatments for RP-CME included oral and topical carbonic anhydrase inhibitors (CAIs), systematic and local steroids, anti-VEGF therapy, NSAIDS, grid LASER photocoagulation, subliminal micropulse LASER, vitrectomy, lutein supplement and oral minocycline. Results: Thirty-two studies were included in the current systematic review and 7 studies were used for meta-analysis. ![]() The secondary outcomes included fluorescein angiography (FA) leakage, rebound of CME and adverse effects. ![]() The primary outcomes included the change of central macular thickness (CMT) and best-corrected visual acuity (BCVA) from baseline. Review manager (Revman) was used to pool the data. The RoB 2 tool was used to evaluate the risk of bias of randomized controlled trials (RCTs), and the MINORS scale was used to assess the methodological quality of non-RCTs. Only studies published in English were included. , WHO ICTRP and ISRCTN were also searched for relevant studies. Methods: PubMed, Embase and the Cochrane library were searched from inception to August 2021. We performed a systematic review and meta-analysis to evaluate the efficacy and safety of current treatments for RP-CME. 5Key Laboratory of Yunnan Province for the Prevention and Treatment of Ophthalmic Diseases, Yunnan Eye Institute, Kunming, Chinaīackground: To date, various treatments for cystoid macular edema (CME) in retinitis pigmentosa (RP) have been reported.4Yunnan Clinical Medicine Center for Ocular Disease, Yunnan Eye Institute, Kunming, China.3Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, China.2Beijing Ophthalmology and Visual Science Key Laboratory, Beijing Institute of Ophthalmology, Beijing, China.1Department of Ophthalmology, The Second People's Hospital of Yunnan Province (Affiliated Hospital of Yunnan University, Fourth Affiliated Hospital of Kunming Medical University), Kunming, China.Chen Chen 1,4,5, Xia Liu 1,4,5 and Xiaoyan Peng 2,3 * ![]() ![]() ![]() The Sage was recommended to us by good friends. Conveniences include desks and complimentary weekday newspapers, as well as phones with free local calls. Private bathrooms with bathtubs or showers feature complimentary toiletries and hair dryers. Wired and wireless Internet access is complimentary, while 40-inch flat-screen televisions with satellite programming provide entertainment. A roundtrip airport shuttle is complimentary (available 24 hours).Make yourself at home in one of the 209 guestrooms featuring refrigerators and microwaves. Planning an event in Santa Fe? This hotel has facilities measuring 7500 square feet (697 square meters), including conference space. Full breakfasts are available daily from 6:30 AM to 10:30 AM for a fee.Featured amenities include complimentary wired Internet access, a business center, and limo/town car service. This hotel also features gift shops/newsstands, a fireplace in the lobby, and a picnic area.Grab a bite to eat at The Bistro, a bistro which features a bar/lounge, or stay in and take advantage of the room service (during limited hours). ![]() This hotel is 0.8 mi (1.3 km) from Meow Wolf and 4.7 mi (7.5 km) from Loretto Chapel.Take advantage of recreation opportunities such as an indoor pool, or other amenities including complimentary wireless Internet access and concierge services. But if you are open to unusual, weird, fun experiences you will be happy- as was I- that you went.Įvidently there are two other Meow Wolf facilities out there but according to people who have been to all three the original Santa Fe Meow Wolf is the best.Santa Fe | 0.77km from Meow Wolf Santa Fe With a stay at Courtyard by Marriott Santa Fe, you'll be centrally located in Santa Fe, within a 10-minute drive of Santa Fe Plaza and Theaterwork Studio. ![]() If flashing lights and dark spaces aren't your jam- don't go. If crowds bother you- don't go- you are often in tight spaces (you can come out of a refrigerator or dive into a washing machine. ![]() Basically is is a huge folk art exhibit with interactive activities, lots of black light sections (my favorite was under the sea), and interesting rooms with things that you could touch and pick-up. The facility seems quite large (I think it was previously a bowling alley) but it's because it wraps around itself and is a double decker. The attendees ranged from infants (a sign says baby wearing is acceptable) to someone that I was pretty sure was in her 90s. It is really efficiently organized, wait lines are clearly marked by signs, Meow Wolf staff members are quite nice, and the other people in line were very friendly. I was extremely hesitant going to Meow Wolf after a quick look online- being a "mature" adult I was pretty sure it was out of my wheelhouse- but my daughter convinced me that it was something we needed to experience while in Santa Fe. Also, as others have mentioned, paying for the prismatic glasses was complete waste of money. But we spent maybe 90 minutes before crowds simply exhausted us. Many amazing immersive environments (including a domed hang out space that reeked so strongly of BO we wondered if it was intentional!). I know there is a storyline if you spend time taking in all details (like reams of paper to read, plus videos with backstory and computer terminals to scan), but there was no room to dive deep given the crowds. Would have been SO much cooler if they limited crowds, or organized entry so only small groups entered at one time (or if crowds on first part of “house” were controlled. Before you can “discover” its various surprises you’ve seen 20 people “discover” them. The problem is the space is meant to be explored and discovered and that’s just not possible when the place is packed when you enter. Booked late afternoon mod-week after reading we might experience lower crowds at that time. Had a great time at Meow Wolf but temper expectations. ![]() ![]() On 6 April, she reached 700,000 YouTube subscribers. On 15 January, she reached 600,000 YouTube subscribers. Coincidentally, Takanashi Kiara reached that same threshold later that day. On 23 November, she reached 500,000 YouTube subscribers, making her the 22nd hololive member to reach this milestone. On 15 November, she debuted her fourth 2D costume during a stream, in this costume Shion wears a black gothic dress with cat ears and tail, the dress is decorated with various ribbons with the appearance of chains, including one tied to her neck, the eye that decorated her hat in her original outfit is now in the chest area of her dress, similar to her second 2D costume her hair is styled with ponytails but unlike that costume, in this one she doesn't have buns, finally the tradicional green and yellow triangles that all of her costumes have, are now only referenced as she wears triangle earrings. On 16 October, hololive's Twitter account announced that Shion, Houshou Marine, Shirogane Noel and Yuzuki Choco would get new 2D costumes. ![]() She debuted her updated model during a stream later the same day, featuring more facial expressions, her hair bangs have more movement, in her hat the tip and the "eyelashes" of the eye were added a bit of movement, along with general movement improvements. On 28 July, she announced on her Twitter account that her original 2D model would be get an update. On 24 January along with the other hololive girls up to the third generation, she debuted her 3D idol outfit at hololive's 1st fes. On 2 January, she announced on her Twitter account that she would get her third 2D costume, this was revealed to be a kimono celebrating the new year later the same day during a stream on YouTube. On 26 August, she revealed her 3D model swimsuit on a stream. On 1 August, she debuted her second 2D costume. The 3D model was later revealed on 12 May. ![]() On 7 May, she announced in a stream that she would debut her 3D model. Her Twitter account was opened on 1 August 2018 while her YouTube channel was created on 3 August although her YouTube activities did not start until her first stream that was live on 17 August. ![]() One of her most iconic cries is her guttural scream of "NEEEEEEE." This was most famously uttered by Shion after Natsuiro Matsuri revealed that Shion's wet sneezing sounds were heard by Matsuri's listeners in one of her livestreams. She has a friendly rivalry with Minato Aqua, and the two can often be seen playing petty and mostly harmless pranks on each other. She wants to be seen as an adult, but thanks to her childish appearance and mannerisms, all attempts by Shion to appear adult-like end up looking very silly. Shion is a smug, cheeky brat (" kusogaki") who speaks bluntly without the usual politeness/consideration associated with the Japanese language, and flirts shamelessly with other hololive members. She can barely say her greeting, “Hellshio”. She calls herself a highborne black magician (probably). A random self-proclaimed child (though she is probably an adult) who appears around the Demonic-Realm Academy. ![]() ![]() Sunday, May 28, 2023.Real-time NFL Football scores on ESPN. Follow along for updates from the NFL Week 18 matchup to decide the AFC South champion.The Michigan Panthers open a three-game road stint against the New Jersey Generals in Canton, Ohio, at 5:30 p.m. The Sporting News tracked live scores and highlights from Saturday's game between the Titans and Jaguars. This game is OVER.The Chiefs are headed back to the Super. Chiefs live updates, highlights from 2023 AFC championship (All times Eastern) Final: Chiefs 23, Bengals 20. WEEK 4: Panthers lose, 29-10, to Memphis Showboats in second game at Ford Field. WEEK 5: Panthers struggle on offense in 23-7 loss to Pittsburgh Maulers. cheap air force 1 The official source for NFL news, video highlights, fantasy football, game-day coverage, schedules, stats, scores and more.Line: Stallions by 5. Each of this weekend's four USFL games will air nationally. MORE: USFL odds, picks, predictions for Week 7: Stallions, Stars, Generals among best bets Week 7 USFL games TV channels, live streams.xfinity cahtFast, updating NFL football game scores and stats as games are in progress are provided by .1 day ago Follow along for updates from the NFL Week 18 matchup to decide the AFC South champion. The Sporting News tracked live scores and highlights from Saturday's game between the Titans and Jaguars.Jayson finished with 33 points, 11 rebounds and 7 assists. The Celtics come away with a 116-99 win. Heat live score, updates, highlights from Game 4 (All times Eastern.) 10:53 p.m. White of SportsLine points out, there are just 15 NFL games with spreads of at least 19.5 in the Stathead database, starting with the 1985 Bears going off as 19.5-point favorites. Game 1: Knicks 101, Cavaliers 97 Game 2: Cavaliers 107, Knicks 90 Game 3: Knicks 99, Cavaliers 79 Game 4: Knicks 102, Cavaliers 93 Game 5. The Wall Street Journal's sources say NBCUniversal paid $110 million for. football cleats stores near me supercuts time warner cable specials Fast, updating NFL football game scores and stats as games are in progress are provided by is getting an exclusive NFL playoff game that won't be available anywhere other than through the online service. 23 when the Buffalo Bills face the Los Angeles. Under the NFL's 11-year contract with NBCUniversal that began this season, Peacock has an exclusive regular-season game.Texas A&M Aggies College Baseball game, final score 4-5, from on ESPN. Texas A&M Aggies College Baseball game, final score 4-5, from on ESPN.The official source for NFL news, video highlights, fantasy football, game-day coverage, schedules, stats, scores and more.Game summary of the Arkansas Razorbacks vs. Follow along for updates from the NFL Week 18 matchup to decide the AFC South champion.Game summary of the Arkansas Razorbacks vs. Stay notified, download the Sports app The Sporting News tracked live scores and highlights from Saturday's game between the Titans and Jaguars. The official source for NFL news, video highlights, fantasy football, game-day coverage, schedules, stats, scores and more.The official source for NFL news, video highlights, fantasy football, game-day coverage, schedules, stats, scores and more. San Diego State Aztecs College Softball game, final score 10-1, from on ESPN. Stream Monday Night Football on ESPN+ and play Fantasy Football.Sports News, Scores, Fantasy Games. ESPN.Visit ESPN for NFL live scores, video highlights and latest news. Hutchinson discusses winning big in Detroit, the pressure that comes with being the hometown hero, beating Aaron Rodgers in his final game as a Packer and his …Hutchinson discusses winning big in Detroit, the pressure that comes with being the hometown hero, beating Aaron Rodgers in his final game as a Packer and his …Pick #2. Stream Monday Night Football on ESPN+ and play Fantasy Football. Stay notified, download the Sports appVisit ESPN for NFL live scores, video highlights and latest news. ![]() ![]() ![]() Southwest's performance drew recrimination from its employees. "This forced daily changes to our flight schedule at a volume and magnitude that still has the tools our teams use to recover the airline operating at capacity." "We were fully staffed and prepared for the approaching holiday weekend when the severe weather swept across the continent, where Southwest is the largest carrier in 23 of the top 25 travel markets in the U.S," the company said. The company was working to address its issues "by rebalancing the airline and repositioning crews," the statement said. In a statement Friday afternoon, Southwest apologized for the cancellations and called them "unacceptable." The city of Houston also was providing buses to passengers looking to leave the airport, officials said. In particular, the company's system of reassigning pilots and crews to new flights didn't have enough people to answer the phones and move the employees, officials said. The company said it would also pay for hotel rooms, rental cars and transportation for people stranded in Houston for the week.ĭuring a press briefing Monday night, a Southwest Airlines representative said the company was overwhelmed by flight cancellations caused by last week's winter storm. People in line were encouraged to go home if they live in Houston. At 6:40 p.m., Southwest announced it would not be able to rebook flights until Dec. The cancellation caused hundreds of people to wait in line to try to rebook their flights. Nationally, the company canceled 2,700 flights Friday. All of the canceled flights were Southwest planes, according to the website. That's in addition to the more than 215 flights to and from Hobby Airport canceled Monday. More than 150 flights to and from Hobby Airport were canceled Tuesday, according to FlightAware, a flight tracking website. MORE ON HOUSTONCHRONICLE.COM: Iconic Port Isabel lighthouse shining brightly for first time in 117 years There have been no disturbances reported at the airport, Bernal said. ![]() Houston Airports spokesman Augusto Bernal said the emergency was called because of the number of people in the airport terminals and in baggage claim. ![]() ![]() ![]() It explains the affront caused to the rule of law and it concludes that the appropriate course of action is for the Government to withdraw the retrospective aspect of the provisions as the Finance Bill goes through Parliament. It questions the lawfulness of the Government’s proposals and it doubts their wisdom: the Chancellor was badly advised by his officials. ![]() This article provides a critique of the retrospectivity of the anti-forestalling provisions of the change to the Entrepreneurs Relief lifetime limit. ![]() But no-one seriously expected the next 2 1/2 pages of the draft legislation to be taken up with retrospective so-called “anti-forestalling” provisions (designed to defeat pre-Budget planning by those wishing to take advantage of the £10m lifetime limit whilst it still remained in force, in advance of the announcement of its reduction). It takes only 5 lines in the published draft legislation to reduce the Entrepreneurs Relief cap to £1m. So the decision to cap the relief at a lifetime limit of £1m (down from £10m) was expected. As the Prime Minister recently commented, “…there are some people who are staggeringly rich who are using that relief to make themselves even more staggeringly rich.” It was widely predicted that the Chancellor would take steps in the Budget to reform Entrepreneurs Relief, which has been widely criticised for years for failing to meet its intended policy objective of encouraging entrepreneurship whilst at the same time being very expensive for the Exchequer. ![]() ![]() ![]() We have a unique understanding of the digital games space, connecting more than 70 million daily active players worldwide. Bubble Trouble Game DownloadHow to Download the Old To Download The Game: https://gplink. Our Miniclip franchises include 8 Ball Pool, Subway Surfers, Golf Battle, Football Strike, Carrom Pool, and Agar.io which have generated more than 7 billion downloads. 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The qualifying direct deposit must be from your employer, payroll provider, gig economy payer, or benefits payer by Automated Clearing House (ACH) deposit OR Original Credit Transaction (OCT). Banks are not responsible for the accuracy of any content provided by author(s) or contributor(s).ġ To apply for Credit Builder, you must have received a single qualifying direct deposit of $200 or more to your Chime Checking Account. Opinions, advice, services, or other information or content expressed or contributed here by customers, users, or others, are those of the respective author(s) or contributor(s) and do not necessarily state or reflect those of The Bancorp Bank, N.A. We recommend you review the privacy statements of those third party websites, as Chime is not responsible for those third parties' privacy or security practices. The privacy practices of those third parties may differ from those of Chime. 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